CMIC Structural Biology Core

Overview of Services

The CMIC Structural Biology Core (SBC) provides state-of-the art equipment to investigate the structures of biomolecules, including those implicated in the etiology of cancer. The SBC supports development and execution of projects that use macromolecular X-ray crystallography and cryo-EM. The core also facilitates access to computational resources needed for structural projects.

Instrumentation for X-ray Crystallography:

• Mosquito LCP liquid-handling crystallization screening robot (Room-temperature)
• Formulatrix Rock Imager 1000 crystallization plate-incubator and imaging hotel at 20° C
• Benchtop variable temperature crystallization plate-incubator
• Zeiss stereomicroscope (Room Temperature)
• Cold room Mosquito Xtal3 liquid-handling crystallization screening robot (4° C)
• Cold room Leica stereomicroscope (4° C)

Instrumentation for Cryo-EM Grid Preparation:

• Vitrobot Mark IV plunge freezer
• Leica GP2 plunge freezer
• PELCO easiGlow™ Glow Discharge Cleaning System
• Biocomp gradient station and fractionation system (gluataraldeyde fixation system)

Facilitate Access to Synchrotron Beamlines and Cryo-Electron Microscopes:

• Assitance in submission of user requests to national and regional facilites

Computer Resources for Cryo-EM Analysis and Structure Prediction:

• 2 8XGPU computer servers housed in the UAMS Primary Data Center
• 1 532 TB storage server housed in the UAMS Primary Data Center (primary storage)
• 1 532 TB storage server housed in the UAMS Secondary Data Center (automated sync of primary storage) 

Leadership

Robert Eoff, Ph.D., Director
Department of Biochemistry & Molecular Biology
Center for Molecular Interactions in Cancer

RLEoff@uams.edu
Office: 501-686-8343
Lab: 501-603-1004

Location and hours of operation

Links and Resources

Terms & Conditions

 UAMS CUSTOMER TERMS AND CONDITIONS FOR RESEARCH CORE FACILITIES SERVICES.

Contacts