Experimental Pathology Core

The Experimental Pathology core is experiencing a substantial backlog of service requests along with an increasing number of new requests. We are working hard to catch up, but it will take some time to do so. In the interim, we will need to prioritize services, and there may be significant delays in completing service requests. We appreciate your patience as we work through the backlog and return to normal operations. Feel free to reach out if you have any questions.

Overview of Services

The UAMS Experimental Pathology (ExPath) Core Laboratory provides researchers with centralized, comprehensive histological services. The laboratory can process and section tissues for use in biochemical, molecular, and pathologic studies. In addition, the laboratory works with investigators to develop immunostaining approaches to detect specific targets of interest and to identify clinical pathologists who can assist with image analysis and data interpretation. The laboratory director, consultants, and technicians have extensive experience in routine histology and immunohistochemistry involving human and animal tissues.

Services and Equipment

  • Tissue Processing and Embedding: The laboratory can process and paraffin embed tissues for downstream analysis. The lab is equipped to section frozen and paraffin-embedded tissues. Sections can be prepared for slides, molecular and biochemical studies, and laser capture dissection.
  • Tissue-Tek VIP 6 AI Tissue Processor and Tissue-Tek Embedding Center: For processing and paraffin embedding tissue
  • Microm HM325 Microtome: For sectioning paraffin-embedded tissues
  • Leica CM3050S Cryostat: For sectioning frozen tissue
  • Tissue Staining: The laboratory provides a variety of standard pathological stains for the histochemical analysis of tissues. In addition, the laboratory works with investigators to develop immunostaining approaches for detecting specific targets of interest.
  • Histo-Tek SL: Automated slide stainer for routine Hematoxylin and Eosin tissue staining
  • Leica Bond-Rx Fully Automated Research Stainer: Stainer that is capable of automated single and multiplexed immunostaining protocols.
  • Slide Scanning and Imaging: The laboratory is equipped with an Aperio digital slide scanner that can capture whole-slide images at 20x and 40x for subsequent analysis and archiving. In addition, the laboratory has an Akoya Mantra™ multispectral imaging system for capturing images with up to seven different colors on a single slide.
  • Leica (Aperio) Scanscope CS2: Has a five-slide capacity and can scan a whole slide at 20X or 40x magnification. Images are stored on a server where they can be shared and analyzed remotely.
  • Mantra™ Quantitative Pathology Workstation: Microscope equipped with a multispectral camera for multiplexed immunohistochemistry and imaging. inForm® Image Analysis software can spectrally unmix signals from 9 different fluorophores.
  • Consultation: Project planning is facilitated by consultation with investigators before project submission to the ExPath laboratory. ExPath staff can assist with antibody selection and optimization, protocol development, and troubleshooting. In addition, investigators can consult with clinical pathologists regarding data analysis and interpretation. 


Dr. Steven Post
Laboratory Director

Jennifer James
Laboratory Manager

Location and hours of operation

Hours     Location

Monday - Friday from 8:00 am - 4:30 pm 

    4301 West Markham Street, Mail Slot 753
    Little Rock, AR 72205
    Lab located at WRCI-Walker Tower Bldg. Room 429

Links and Resources

  1. UAMS Webpage


Terms & Conditions



Name Role Phone Email Location
Dr. Steven Post
Laboratory Director

Dr. Matt Quick
Clinical Director

Jennifer James
Laboratory Manager
WRCI Room 429 (Walker Tower Bldg.)
Erin Bartels
Research Program Manager



Service list

Search available services: View: by category alphabetically
Histology (8)
Consultation (1)
Digital Slide Scanning (3)
Cryostat Instrument (2)